Bacteriophage deoxyribonucleic acid-induced mutation of Streptococcus mutans

Deoxyribonucleic acid repair in bacteriophage.

Ultraviolet Light Induced Mutation and Deoxyribonucleic Acid Replication in Bacteria.

HE terminal process through which the genetic change induced by ultraviolet Tlight (UV) is incorporated into the genetic apparatus is the initial postirradiation deoxyribonucleic acid (DNA) replication ( HAAS and DOUDNEY 1959; DOUDNEY and HAAS 1960). It has been suggested that two discrete radiation effects are prerequisite to incorporation of the “potential mutation” into DNA ( DOUDNEY, KADA a...

Separation of T-even bacteriophage deoxyribonucleic acid from host deoxyribonucleic acid by hydroxyapatite chromatography.

A simple and rapid method is described for separation of T-even bacteriophage deoxyribonucleic acid (DNA) from host (Escherichia coli) DNA by hydroxyapatite column chromatography with a shallow gradient of phosphate buffer at neutral pH. By this method, bacteriophage T2, T4, and T6 DNA (but not T5, T7, or lambda DNA) could be separated from host E. coli DNA. It was found that glucosylation of t...

Equal incorporation of both parental bacteriophage T7 deoxyribonucleic acid strands into intracellular concatemeric deoxyribonucleic acid.

After infection of Escherichia coli B with radiolabeled T7 bacteriophage, the parental deoxyribonucleic acid label was found in both polynucleotide chains of the intracellular T7 concatemer.

Biochemistry of Deoxyribonucleic Acid-defective Amber Mutants of Bacteriophage TP

Nucleotide pools were analyzed under different conditions of infection by bacteriophage T4, for three reasons: (a) as an approach to identifying the defective functions associated with conditional lethal phage mutants bearing uncharacterized lesions in DNA replication; (b) to gain information about the control of nucleotide synthesis in phage-infected Escherichia coli; and (c) as an aid to inte...